Item 5.02 Departure of Directors or Principal Officers; Election of Directors;
Appointment of Principal Officers; Compensatory Arrangements of Certain Officers.

(d) Effective as of January 5, 2009, Unigene Laboratories, Inc. (the "Company") increased the size of its Board of Directors (the "Board") from nine to ten and elected Zvi Eiref to serve as a director of the Company. The Board plans to appoint Mr. Eiref to serve on one or more committees of the Board in early 2009. Mr. Eiref will receive an option to purchase 30,000 shares of the Company's common stock, which option will vest in equal installments of 1/3 over a period of three years and such other compensation in accordance with the Company's director compensation policies. The Company issued a press release announcing the foregoing, a copy of which is attached hereto as Exhibit 99.1 and is incorporated herein by reference.

Item 9.01 Financial Statements and Exhibits.

(d) Exhibits.

Exhibit No. Document Description
99.1 Press Release dated January 7, 2009

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